Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | TACR1 | P25103 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CRACR2A | Q9BSW2 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738140 | 0.82 | HSP90AA1 (0.38) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL9737730 | 0.80 | TLR8 (0.35) | TLR8HCRTR1HCRTR2CRACR2AKDM4E | |
| SCHEMBL9739162 | 0.78 | MAPK14 (0.38) | TLR8HCRTR1HCRTR2CRACR2ATRPV1 | |
| SCHEMBL9737369 | 0.77 | MAPK14 (0.40) | TLR8CRACR2ATRPV1RXFP1KDM4E | |
| SCHEMBL9739960 | 0.69 | HSP90AA1 (0.39) | CYP3A4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9739285 | 0.67 | CYP3A4 (0.39) | CYP3A4RXFP1 | |
| SCHEMBL30531475 | 0.65 | PDK1 (0.44) | TLR8KDM4EALDH1A1GAAMAPT | |
| SCHEMBL10400743 | 0.64 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9739910 | 0.63 | PDE4B (0.35) | CYP3A4TRPV1ALDH1A1GAAHPGD | |
| SCHEMBL9738579 | 0.63 | PRKD3 (0.43) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |