Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207602 | 0.79 | ALOX5 (0.43) | ALOX5SRD5A2HTR3A | |
| SCHEMBL9738046 | 0.77 | ALOX5 (0.45) | ALOX5SRD5A2NPC1RAB9AHTR3A | |
| SCHEMBL2019619 | 0.74 | YAP1 (0.41) | ALOX5SRD5A2HTR3A | |
| SCHEMBL9215265 | 0.70 | LIPG (0.49) | — | |
| SCHEMBL9737780 | 0.70 | SRD5A2 (0.47) | SRD5A2 | |
| SCHEMBL9488819 | 0.69 | FFAR1 (0.51) | — | |
| SCHEMBL9491758 | 0.69 | MAOA (0.47) | — | |
| SCHEMBL2018985 | 0.68 | S1PR1 (0.47) | — | |
| SCHEMBL2021908 | 0.68 | NOTUM (0.55) | ALOX5SRD5A2NPC1RAB9A | |
| SCHEMBL9060909 | 0.68 | ALOX5 (0.49) | ALOX5NPC1RAB9APARP10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021678-A1 | LIPOXYGENASE INHIBITING PYRROLO [1,2a]INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | disclosed |