Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840999 | 0.93 | ACHE (0.47) | ACHEBCHEGAAHTR1AHTR7 | |
| SCHEMBL8840949 | 0.90 | ACHE (0.43) | ACHEBCHEHTR1AHTR7HTR6 | |
| SCHEMBL9737830 | 0.89 | APP (0.40) | ACHEBCHEGAAMAPTALDH1A1 | |
| SCHEMBL9738208 | 0.84 | GAA (0.34) | GAAMAPTSRCALDH1A1POLB | |
| SCHEMBL8840973 | 0.82 | ACHE (0.48) | ACHEBCHEHTR1AHTR7HTR6 | |
| SCHEMBL9738376 | 0.77 | ACHE (0.42) | ACHEBCHEHTR1AHTR7HTR6 | |
| SCHEMBL9738054 | 0.77 | MAPT (0.41) | GAAMAPTALDH1A1HTTMEN1 | |
| SCHEMBL9739096 | 0.76 | PDE4A (0.40) | ACHEBCHEGAAHTR1AHTR7 | |
| SCHEMBL9738168 | 0.76 | APP (0.41) | GAAMAPTALDH1A1POLBMEN1 | |
| SCHEMBL10365809 | 0.75 | ACHE (0.38) | ACHEGAAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153194-A | Anxiolytic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |