Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738814 | 0.90 | NOS3 (0.35) | CRHBPCRHR2NOS3NOS1NOS2 | |
| SCHEMBL9738049 | 0.77 | CRHBP (0.38) | GAACRHBPCRHR2KDM4EALDH1A1 | |
| SCHEMBL10638215 | 0.73 | ADRA2A (0.40) | GAACRHBPCRHR2KDM4EALDH1A1 | |
| SCHEMBL10500943 | 0.73 | CRHBP (0.36) | GAACRHBPCRHR2ALDH1A1 | |
| SCHEMBL9739029 | 0.72 | L3MBTL1 (0.42) | CRHBPCRHR2NOS3NOS1NOS2 | |
| SCHEMBL9683050 | 0.69 | GAA (0.31) | GAA | |
| SCHEMBL8844371 | 0.66 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL1131131 | 0.66 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL9424547 | 0.66 | PTGS1 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL10395131 | 0.65 | GAA (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086177-A | Chemical intermediate for herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4980469-A | Reacting isothiourea of nitrogen containing heterocycle with hydroxylamine derivative | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |