Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC33A1 | O00400 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739948 | 0.89 | SLC33A1 (0.33) | SLC33A1 | |
| SCHEMBL9738783 | 0.88 | SLC33A1 (0.35) | SLC33A1TRPV1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9738552 | 0.88 | SLC33A1 (0.34) | SLC33A1TRPV1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9739892 | 0.88 | SLC33A1 (0.37) | SLC33A1 | |
| SCHEMBL9553055 | 0.87 | SLC33A1 (0.36) | SLC33A1ALDH1A1TSHRL3MBTL1TRPV1 | |
| SCHEMBL9553031 | 0.85 | SLC33A1 (0.36) | SLC33A1ALDH1A1TRPV1KCNJ6KCNJ5 | |
| SCHEMBL9553453 | 0.83 | ALDH1A1 (0.36) | SLC33A1ALDH1A1TSHRSMN1; SMN2TRPV1 | |
| SCHEMBL9553197 | 0.83 | SLC33A1 (0.35) | SLC33A1ALDH1A1TSHRSMN1; SMN2TRPV1 | |
| SCHEMBL9552275 | 0.83 | SLC33A1 (0.34) | SLC33A1TRPV1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9739362 | 0.83 | SLC33A1 (0.34) | SLC33A1ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |