Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737076 | 0.87 | MAPK14 (0.43) | LMNAHSP90AA1HSP90AB1MAPK14ALDH1A1 | |
| SCHEMBL9740354 | 0.84 | MAPK14 (0.39) | LMNAHSP90AA1HSP90AB1MAPK14ALDH1A1 | |
| SCHEMBL9738360 | 0.83 | MAPK14 (0.41) | LMNAHSP90AA1HSP90AB1MAPK14CD38 | |
| SCHEMBL9737104 | 0.83 | LMNA (0.40) | LMNAHSP90AA1HSP90AB1MAPK14ALDH1A1 | |
| SCHEMBL9737938 | 0.83 | HSP90AA1 (0.38) | LMNAHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL9739960 | 0.82 | HSP90AA1 (0.39) | LMNAHSP90AA1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL9737393 | 0.82 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL9738838 | 0.81 | HSP90AA1 (0.38) | LMNAHSP90AA1HSP90AB1ALDH1A1MEN1 | |
| SCHEMBL9737486 | 0.80 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1ALDH1A1MEN1KMT2A | |
| SCHEMBL9739327 | 0.79 | SDHB (0.39) | LMNAMAPK14ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |