Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737076 | 0.93 | MAPK14 (0.43) | MAPK14GAALMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9740354 | 0.90 | MAPK14 (0.39) | MAPK14CD38LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9737104 | 0.89 | LMNA (0.40) | MAPK14CD38LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL9739327 | 0.84 | SDHB (0.39) | MAPK14GAACD38NPC1RAB9A | |
| SCHEMBL9738307 | 0.83 | LMNA (0.37) | MAPK14GAACD38LMNAHSP90AA1 | |
| SCHEMBL9739162 | 0.83 | MAPK14 (0.38) | MAPK14PRKD3CLK2DYRK1APRKD2 | |
| SCHEMBL9739960 | 0.81 | HSP90AA1 (0.39) | PRKD3CLK2DYRK1APRKD2PIM2 | |
| SCHEMBL9739376 | 0.80 | RBP4 (0.39) | CD38HSP90AA1HSP90AB1 | |
| SCHEMBL9738335 | 0.79 | MAPK14 (0.39) | MAPK14PRKD3CLK2DYRK1APRKD2 | |
| SCHEMBL9737938 | 0.77 | HSP90AA1 (0.38) | CD38LMNAHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |