Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 6/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.47 |
| ▸ | PDE5A | O76074 | 3/20 | 0.47 |
| ▸ | PDE1A | P54750 | 3/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739273 | 0.87 | ACP1 (0.49) | FGFR1FGFR4LMNAADORA2AYTHDC1 | |
| SCHEMBL9738831 | 0.84 | FGFR1 (0.50) | FGFR1FGFR4HDAC6ADORA2AADORA1 | |
| SCHEMBL782938 | 0.82 | YTHDC1 (0.53) | FGFR1FGFR4PDE4APDE4BPDE4C | |
| SCHEMBL13732188 | 0.81 | STAT6 (0.52) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL11014177 | 0.80 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL9738952 | 0.80 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL9738442 | 0.80 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL10442248 | 0.79 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| Dimethylamine SCHEMBL4532702 | 0.77 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL1662517 | 0.75 | ADORA1 (0.47) | LMNAADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | claimed |
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |