Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738484 | 0.87 | FGFR1 (0.49) | LMNAYTHDC1FGFR1FGFR4ADORA2A | |
| SCHEMBL782938 | 0.84 | YTHDC1 (0.53) | ACP1YTHDC1FGFR1FGFR4ADORA2A | |
| SCHEMBL9740503 | 0.83 | ACP1 (0.44) | ACP1ALDH1A1USP2CYP1A2CYP2C9 | |
| SCHEMBL9741179 | 0.83 | CCR4 (0.48) | ACP1YTHDC1CCR4CNR2BRD4 | |
| SCHEMBL22345218 | 0.77 | YTHDC1 (0.54) | ACP1ALDH1A1YTHDC1ADORA2ACNR2 | |
| SCHEMBL9738831 | 0.77 | FGFR1 (0.50) | ACP1ALDH1A1TSHRFGFR1FGFR4 | |
| SCHEMBL23093469 | 0.75 | CYP1A2 (0.43) | ALDH1A1USP2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7215799 | 0.74 | CYP11B1 (0.67) | ALDH1A1USP2LMNATSHRBRD4 | |
| SCHEMBL5839419 | 0.73 | FGFR1 (0.40) | ALDH1A1YTHDC1FGFR1FGFR4CCR4 | |
| SCHEMBL29601304 | 0.73 | FGFR1 (0.41) | ALDH1A1FGFR1FGFR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |