Xanthone

Xanthone

SCHEMBL9762833

O=C(c1ccccc1)c1ccccc1.O=c1c2ccccc2oc2ccccc12

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.69
ALDH1A1 P00352 4/20 0.69
MAPT P10636 3/20 0.69
KDM4E B2RXH2 2/20 0.69
CYP3A4 P08684 2/20 0.69
GLA P06280 1/20 0.69
HPGD P15428 1/20 0.69
PGAM1 P18669 1/20 0.69
CASP1 P29466 1/20 0.69
CASP7 P55210 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
HSD17B10 Q99714 1/20 0.69
TTR P02766 4/20 0.65
NPC1 O15118 2/20 0.58
RAB9A P51151 1/20 0.58
KMT2A Q03164 3/20 0.57
CYP2C9 P11712 2/20 0.54
TBK1 Q9UHD2 1/20 0.54
MEN1 O00255 2/20 0.53
LMNA P02545 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242650 0.90 TTR (0.77) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL28077164 0.89 TTR (0.75) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL28434710 0.85 MAOA (0.95) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL30798764 0.85 MAOA (0.95) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL9738572 0.85 NPC1 (0.73) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL18138444 0.84 MAOA (0.75) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL5842358 0.84 MAOA (0.62) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL41161 0.83 MAOA (1.00) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL29398266 0.83 MAOA (1.00) MAOAALDH1A1MAPTKDM4ECYP3A4
Xanthone SCHEMBL29358061 0.83 MAOA (1.00) MAOAALDH1A1MAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019475-A Image recording medium comprising a color developer layer formed on a thermoplastic resin layer BROTHER KOGYO KABUSHIKI KAISHA (JP) 1991-05-28 US disclosed