Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 11/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739561 | 0.87 | PDE4A (0.52) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9741263 | 0.86 | ADORA2A (0.52) | ADORA2AYTHDC1PDE4APDE4BPDE4C | |
| SCHEMBL7204383 | 0.85 | PDE4A (0.62) | ADORA2AYTHDC1PDE4APDE4BPDE4C | |
| SCHEMBL9738081 | 0.84 | YTHDC1 (0.59) | ADORA2AYTHDC1PDE4APDE4BPDE4C | |
| SCHEMBL9738563 | 0.84 | CDK1 (0.55) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9738444 | 0.81 | YTHDC1 (0.56) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9739898 | 0.81 | PDE4A (0.51) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9739774 | 0.79 | ADORA2A (0.55) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9740503 | 0.78 | ACP1 (0.44) | CNR2ACP1 | |
| SCHEMBL9738569 | 0.78 | PDE4A (0.53) | ADORA2AYTHDC1CNR2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |