Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738444 | 0.88 | YTHDC1 (0.56) | ADORA2ATMIGD3ADORA1ADORA2BYTHDC1 | |
| SCHEMBL9739623 | 0.86 | ADORA2A (0.55) | ADORA2ATMIGD3ADORA1ADORA2BYTHDC1 | |
| SCHEMBL7209250 | 0.86 | ADORA2A (0.69) | ADORA2ATMIGD3ADORA1ADORA2BYTHDC1 | |
| SCHEMBL9738222 | 0.84 | PDE4A (0.47) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9738563 | 0.82 | CDK1 (0.55) | ADORA2AADORA1YTHDC1CNR2PDE4A | |
| SCHEMBL23763962 | 0.80 | ADORA2A (0.55) | ADORA2ATMIGD3ADORA1ADORA2BPDE4A | |
| SCHEMBL9738722 | 0.79 | ADORA2A (0.48) | ADORA2AYTHDC1CNR2PDE4APDE4B | |
| SCHEMBL9738741 | 0.78 | ADORA2A (0.53) | ADORA2ATMIGD3ADORA1ADORA2BPDE4A | |
| SCHEMBL7212614 | 0.77 | ADORA2A (0.72) | ADORA2ATMIGD3ADORA1ADORA2BYTHDC1 | |
| SCHEMBL3960757 | 0.76 | CNR2 (0.46) | ADORA2AYTHDC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0363320-A2 | Substituted 9H purine | CIBA-GEIGY AG (CH) | 1990-04-11 | — | — | EP | disclosed |