Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936119 | 0.78 | MAPT (0.46) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL9737428 | 0.76 | KCNH2 (0.59) | KCNH2MAPTCHRNB2CHRNA4POLB | |
| SCHEMBL9753047 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CYP1A2MAPTLMNAHTT | |
| SCHEMBL9675487 | 0.73 | CDC25C (0.55) | ALDH1A1KCNH2 | |
| SCHEMBL6231424 | 0.72 | TTR (0.43) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL6231422 | 0.72 | TTR (0.43) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL14127817 | 0.71 | KDM4E (0.55) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL12130515 | 0.70 | CA1 (0.48) | ALDH1A1CYP3A4KCNH2MAPTLMNA | |
| SCHEMBL10534058 | 0.69 | NPC1 (0.46) | ALDH1A1MAPTLMNANPSR1HTT | |
| SCHEMBL27200602 | 0.69 | RIPK1 (0.43) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |