Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 11/20 | 0.43 |
| ▸ | TUBB | P07437 | 11/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 11/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 11/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 11/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 11/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 11/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 11/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 11/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 11/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 11/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 11/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 11/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 11/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740681 | 0.79 | ABCB1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9741666 | 0.75 | CYP1A2 (0.46) | MEN1CYP3A4CYP2C19KMT2ACALM1 | |
| SCHEMBL9740060 | 0.75 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1539241 | 0.73 | CA1 (0.39) | MEN1ALDH1A1CYP3A4TSHRKMT2A | |
| SCHEMBL9741708 | 0.73 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9740073 | 0.73 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9740017 | 0.72 | DHFR (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL21905231 | 0.71 | GPR84 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31436136 | 0.71 | GPR84 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9739295 | 0.69 | TUBB4A (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |