Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220225 | 0.85 | NPC1 (0.47) | NPC1FGFR1JAK2KDM4EMEN1 | |
| SCHEMBL2400449 | 0.75 | TDO2 (0.54) | IMPDH2ALOX5HSD17B10 | |
| SCHEMBL9741544 | 0.74 | TNKS2 (0.49) | KDM4EMEN1MAPTKMT2ATNKS2 | |
| SCHEMBL9740109 | 0.73 | IDH1 (0.42) | MEN1KMT2AGSK3BFEN1LMNA | |
| SCHEMBL1538 | 0.72 | — | — | |
| SCHEMBL9739133 | 0.72 | CDK4 (0.42) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL21494513 | 0.70 | TRPA1 (0.32) | IMPDH2ALDH1A1HSD17B10 | |
| SCHEMBL207535 | 0.69 | AHR (0.42) | FGFR1JAK2IMPDH2CLK2GSK3B | |
| SCHEMBL2955170 | 0.69 | TYR (0.42) | KDM4EMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL6048398 | 0.67 | MAOA (0.43) | NPC1JAK2KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |