Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215737 | 0.92 | DRD2 (0.40) | DRD2CDK9KHKBRD4CHRM2 | |
| SCHEMBL9208356 | 0.85 | GRM5 (0.42) | ITGB3ITGA2BDRD2CDK9KHK | |
| SCHEMBL9212186 | 0.80 | SMN1; SMN2 (0.48) | DRD2CHRM2HTR1ASLC6A4DRD3 | |
| SCHEMBL9204902 | 0.79 | SMN1; SMN2 (0.47) | DRD2CHRM2HTR1ASLC6A4DRD3 | |
| SCHEMBL9208151 | 0.78 | GRM5 (0.44) | ITGB3ITGA2BDRD2CDK9KHK | |
| SCHEMBL9740567 | 0.78 | DRD2 (0.41) | DRD2CDK9KHKKCNH2GRM5 | |
| SCHEMBL9214240 | 0.77 | GRM5 (0.43) | ITGB3ITGA2BDRD2CDK9KHK | |
| SCHEMBL9207567 | 0.77 | DRD2 (0.39) | DRD2CDK9GRM5SMN1; SMN2PARP1 | |
| SCHEMBL9740563 | 0.74 | DRD2 (0.39) | DRD2CDK9KHKKCNH2GRM5 | |
| SCHEMBL9740805 | 0.74 | PARP1 (0.45) | DRD2KHKKDM1AGRM5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |