Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | EBP | Q15125 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739334 | 0.86 | TRPV6 (0.59) | ALDH1A1FKBP1ADRD2POLB | |
| SCHEMBL9741170 | 0.84 | FAAH (0.52) | — | |
| SCHEMBL9739469 | 0.81 | ABCB1 (0.55) | FKBP1AHTTSIGMAR1EBPTMEM97 | |
| SCHEMBL8828191 | 0.79 | SPHK2 (0.58) | ALDH1A1SMN1; SMN2HTTMAPK1DRD2 | |
| SCHEMBL8828199 | 0.79 | SPHK2 (0.58) | ALDH1A1SMN1; SMN2HTTMAPK1DRD2 | |
| SCHEMBL8828287 | 0.77 | MAPK1 (0.53) | ALDH1A1SMN1; SMN2HTTSIGMAR1EBP | |
| SCHEMBL8828284 | 0.77 | MAPK1 (0.53) | ALDH1A1SMN1; SMN2HTTSIGMAR1EBP | |
| SCHEMBL8493415 | 0.77 | MAPK1 (0.54) | ALDH1A1SMN1; SMN2FKBP1ASIGMAR1EBP | |
| SCHEMBL10762114 | 0.76 | FAAH (0.53) | ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8828289 | 0.76 | MAPK1 (0.52) | ALDH1A1SMN1; SMN2HTTSIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |