Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739477 | 0.86 | ALDH1A1 (0.54) | DRD2ALDH1A1POLBFKBP1A | |
| SCHEMBL9740178 | 0.86 | HRH3 (0.48) | HRH3ALDH1A1POLB | |
| SCHEMBL9753176 | 0.84 | HRH3 (0.53) | TRPV6HRH3KCNH2DRD2ALDH1A1 | |
| SCHEMBL9753177 | 0.84 | HRH3 (0.53) | TRPV6HRH3KCNH2DRD2ALDH1A1 | |
| SCHEMBL9739559 | 0.83 | POLB (0.46) | HRH3ALDH1A1POLBFKBP1A | |
| SCHEMBL9208592 | 0.80 | HTR1A (0.50) | — | |
| SCHEMBL9741170 | 0.78 | FAAH (0.52) | KCNH2 | |
| SCHEMBL9372055 | 0.77 | HRH3 (0.68) | TRPV6HRH3 | |
| SCHEMBL9372067 | 0.77 | HRH3 (0.68) | TRPV6HRH3 | |
| SCHEMBL9374317 | 0.77 | HRH3 (0.68) | TRPV6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |