Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 16/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739605 | 1.00 | MMP2 (0.51) | MMP2MMP9MMP8IDEREN | |
| SCHEMBL9741586 | 0.90 | MMP2 (0.51) | MMP2MMP9MMP8IDEREN | |
| SCHEMBL9741583 | 0.90 | MMP2 (0.51) | MMP2MMP9MMP8IDEREN | |
| SCHEMBL9740882 | 0.81 | MMP2 (0.54) | MMP2MMP9MMP8IDEREN | |
| SCHEMBL9740887 | 0.81 | MMP2 (0.54) | MMP2MMP9MMP8IDEREN | |
| SCHEMBL9740313 | 0.77 | REN (0.41) | MMP2MMP9MMP8REN | |
| SCHEMBL9740310 | 0.77 | REN (0.41) | MMP2MMP9MMP8REN | |
| SCHEMBL9740864 | 0.76 | MMP2 (0.55) | MMP2MMP9MMP8REN | |
| SCHEMBL9740857 | 0.76 | MMP2 (0.55) | MMP2MMP9MMP8REN | |
| SCHEMBL9740696 | 0.75 | REN (0.38) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | claimed |