Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213653 | 0.89 | ALDH1A1 (0.45) | ALDH1A1TSHRSLC6A4ABCB1HTR2A | |
| SCHEMBL9212347 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRSLC6A4ABCB1HTR2A | |
| SCHEMBL9212261 | 0.76 | ABCB1 (0.49) | ALDH1A1TSHRSLC6A4ABCB1HTR2A | |
| Hydrochloric Acid SCHEMBL9743101 | 0.70 | HTR1A (0.52) | SLC6A4HTR2AHTR1DHTR1B | |
| SCHEMBL9213552 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TSHRSLC6A4HTR2ABCHE | |
| Hydrochloric Acid SCHEMBL10649415 | 0.64 | HTR1A (0.56) | SLC6A4HTR2AHTR1DHTR1B | |
| SCHEMBL11222881 | 0.63 | SIGMAR1 (0.63) | TSHRSIGMAR1 | |
| SCHEMBL7004405 | 0.62 | HTR2A (0.73) | ALDH1A1TSHRSLC6A4HTR2ALMNA | |
| Water SCHEMBL9739470 | 0.62 | HTR1A (0.45) | SLC6A4HTR2ABCHEACHEHTR1D | |
| Hydrochloric Acid SCHEMBL9741109 | 0.62 | PDE4D (0.49) | SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |