Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.51 |
| ▸ | CTSS | P25774 | 8/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449644 | 0.81 | CTSS (0.44) | RENCTSSCTSLCTSK | |
| SCHEMBL4454183 | 0.81 | CTSS (0.44) | RENCTSSCTSLCTSK | |
| SCHEMBL6062505 | 0.79 | CTSS (0.52) | CTSSCTSLCTSK | |
| SCHEMBL6062496 | 0.79 | CTSS (0.52) | CTSSCTSLCTSK | |
| SCHEMBL4459425 | 0.78 | CTSS (0.47) | RENCTSSCTSLCTSK | |
| SCHEMBL6876245 | 0.74 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL8350092 | 0.73 | TSHR (0.47) | CTSS | |
| SCHEMBL4044979 | 0.73 | TSHR (0.47) | CTSS | |
| SCHEMBL9622591 | 0.71 | LTA4H (0.52) | REN | |
| SCHEMBL9622584 | 0.71 | LTA4H (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |