Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622584 | 1.00 | LTA4H (0.52) | LTA4HALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL8773913 | 0.82 | LTA4H (0.49) | LTA4HKMT2AFNTAFNTBPGGT1B | |
| SCHEMBL11407261 | 0.80 | METAP2 (0.51) | ALDH1A1MEN1LMNAKMT2AREN | |
| SCHEMBL7361186 | 0.80 | METAP2 (0.51) | ALDH1A1MEN1LMNAKMT2AREN | |
| SCHEMBL11407267 | 0.80 | METAP2 (0.51) | ALDH1A1MEN1LMNAKMT2AREN | |
| SCHEMBL9067212 | 0.79 | LTA4H (0.47) | LTA4HALDH1A1KMT2AFNTAFNTB | |
| Hydrochloric Acid SCHEMBL7508388 | 0.79 | METAP2 (0.50) | ALDH1A1MEN1LMNAKMT2AREN | |
| SCHEMBL3165087 | 0.78 | CPB2 (0.50) | LTA4HFNTAFNTBPGGT1BREN | |
| SCHEMBL31433203 | 0.77 | CPB2 (0.47) | LTA4HALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4313039 | 0.77 | ALDH1A1 (0.51) | LTA4HALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |