Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711268 | 0.81 | IDO1 (0.41) | ALDH1A1TDP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL4368894 | 0.77 | ALDH1A1 (0.53) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11698159 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL30753695 | 0.75 | MTNR1A (0.62) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2284298 | 0.75 | MTNR1A (0.62) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11986310 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8444448 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9740256 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1TDP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9739624 | 0.73 | LMNA (0.46) | ALDH1A1TDP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL8746025 | 0.73 | MAPT (0.37) | ALDH1A1TDP1L3MBTL1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |