Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927087 | 0.81 | HTR2C (0.34) | HTR2C | |
| SCHEMBL8793023 | 0.80 | SIRT2 (0.39) | HTR2CSIRT2 | |
| SCHEMBL8794212 | 0.77 | HTT (0.32) | HTR2C | |
| SCHEMBL8792741 | 0.76 | TSHR (0.38) | HTR2C | |
| SCHEMBL1123239 | 0.75 | KDM4E (0.44) | HTR2C | |
| SCHEMBL1122649 | 0.75 | KDM4E (0.44) | HTR2C | |
| SCHEMBL3349385 | 0.75 | KDM4E (0.44) | HTR2C | |
| SCHEMBL8473555 | 0.71 | S100A4 (0.35) | HTR2C | |
| SCHEMBL22868095 | 0.70 | KDM4E (0.40) | SIRT2 | |
| SCHEMBL9739615 | 0.69 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091409-A | Useful in treatment of ocular hypertension and glaucoma | MERCK & CO., INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0457586-A1 | 4-alkylamino-6-(C3-5-hydrocarbyl)thieno [2,3-B] thiopyran-2-sulfonamide-7,7-dioxides | MERCK & CO. INC. (US) | 1991-11-21 | — | — | EP | disclosed |