Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740778 | 0.78 | ALOX5 (0.36) | — | |
| SCHEMBL9739267 | 0.75 | MAPT (0.33) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL9740058 | 0.74 | MAPT (0.37) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL9740244 | 0.74 | MAPT (0.58) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL9738964 | 0.66 | KMT2A (0.53) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL9740472 | 0.64 | GAA (0.59) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL207534 | 0.63 | AHR (0.48) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL20481932 | 0.63 | MEN1 (0.45) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL6354139 | 0.62 | GAA (0.43) | GAA | |
| SCHEMBL22462465 | 0.60 | ALDH1A1 (0.31) | LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |