Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739500 | 0.82 | HCN4 (0.41) | SMN1; SMN2GAAABCB1HCN4CHRM2 | |
| SCHEMBL9739396 | 0.81 | MAOA (0.35) | KCNH2HRH3MAOAMAOB | |
| SCHEMBL9740238 | 0.81 | ABCB1 (0.42) | SMN1; SMN2GAAACHEBCHEABCB1 | |
| Hydrochloric Acid SCHEMBL9740197 | 0.80 | CYP3A4 (0.42) | SMN1; SMN2GAAACHEBCHEABCB1 | |
| SCHEMBL9739180 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAABCB1HCN4DRD3 | |
| SCHEMBL9740418 | 0.79 | ABCB1 (0.46) | SMN1; SMN2GAAABCB1HCN4HRH3 | |
| Hydrochloric Acid SCHEMBL9740153 | 0.78 | ABCB1 (0.45) | SMN1; SMN2GAAABCB1HCN4HRH3 | |
| SCHEMBL9739027 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2GAAHCN4CHRM2HTR1A | |
| SCHEMBL9740219 | 0.78 | HCN4 (0.49) | SMN1; SMN2GAAHCN4MAPTCYP3A4 | |
| SCHEMBL9739355 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2GAAHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |