Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738870 | 0.82 | APLNR (0.42) | APLNRIDO1GPR84CA2CA12 | |
| SCHEMBL310518 | 0.82 | ALDH1A1 (0.47) | GPR84CA2CA12CA1CA7 | |
| SCHEMBL9741596 | 0.80 | TUBB1 (0.56) | — | |
| SCHEMBL11307947 | 0.74 | HSD17B10 (0.47) | TDP1ALDH1A1MAPT | |
| SCHEMBL6741447 | 0.72 | APLNR (0.51) | APLNRIDO1HDAC8CA2CA12 | |
| SCHEMBL11571607 | 0.70 | APLNR (0.53) | APLNRIDO1CA2CA12CA1 | |
| SCHEMBL9740914 | 0.69 | TUBB1 (0.56) | ALDH1A1 | |
| SCHEMBL1968319 | 0.69 | MEN1 (0.47) | GPR84CA2CA12CA1CA7 | |
| SCHEMBL6016057 | 0.69 | KEAP1 (0.46) | HTR1AALDH1A1MAPT | |
| SCHEMBL4003210 | 0.69 | APLNR (0.63) | APLNRIDO1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |