Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739503 | 0.84 | IDO1 (0.45) | CA2IDO1 | |
| SCHEMBL9740549 | 0.82 | APLNR (0.42) | APLNRGPR84CA2CA12CA1 | |
| SCHEMBL310518 | 0.79 | ALDH1A1 (0.47) | GPR84CA2CA12CA1CA7 | |
| SCHEMBL9739685 | 0.76 | PDE10A (0.44) | APLNRGPR84PDE10ACSF1RNTRK2 | |
| SCHEMBL5612174 | 0.75 | APLNR (0.59) | APLNRCSF1RNTRK2CA2CA12 | |
| SCHEMBL145084 | 0.72 | APLNR (0.68) | APLNRCA2CA12CA1CA7 | |
| SCHEMBL9291320 | 0.70 | MAPK1 (0.61) | APLNRCSF1RNTRK2CA2CA12 | |
| SCHEMBL5612171 | 0.70 | APLNR (0.53) | APLNRPDE10ACA2CA12CA1 | |
| SCHEMBL3300286 | 0.70 | LTA4H (0.58) | APLNR | |
| SCHEMBL1968319 | 0.69 | MEN1 (0.47) | GPR84CA2CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |