Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694423 | 0.78 | ALOX5 (0.62) | MAOBALOX5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9741209 | 0.76 | MAOB (0.36) | CYP2D6MAOBKDM4ENOS1NOS3 | |
| SCHEMBL9740058 | 0.75 | MAPT (0.37) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9740778 | 0.74 | ALOX5 (0.36) | MAOBALOX5MAOAF2 | |
| SCHEMBL1388250 | 0.67 | MAOA (0.50) | MAOBMAOA | |
| SCHEMBL9740911 | 0.65 | TUBB1 (0.57) | MAOBKDM4EALDH1A1HPGD | |
| SCHEMBL315575 | 0.65 | AXL (0.53) | KDM4EALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL6840901 | 0.63 | MRGPRX4 (0.50) | CYP2D6MAOBMAOA | |
| SCHEMBL5830621 | 0.62 | KDM4E (0.58) | KDM4EALDH1A1MAOAPDGFRBPDGFRA | |
| SCHEMBL2971940 | 0.62 | MEN1 (0.47) | KDM4EALDH1A1HPGDHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |