Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739670 | 0.79 | HCN4 (0.55) | ABCB1HTR1ASLC6A4ALDH1A1 | |
| SCHEMBL9739668 | 0.74 | HCN4 (0.54) | SMPD1SIGMAR1ALDH1A1 | |
| SCHEMBL9740380 | 0.74 | HCN4 (0.54) | SMPD1SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10766227 | 0.73 | HCN4 (0.53) | SMPD1 | |
| SCHEMBL9739280 | 0.72 | HCN4 (0.59) | ABCB1SMPD1HTR1ASLC6A4MAPK1 | |
| SCHEMBL9740673 | 0.70 | ABCB1 (0.43) | ABCB1SMPD1HTR1ASLC6A4EBP | |
| Hydrochloric Acid SCHEMBL9738862 | 0.69 | HCN4 (0.44) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9739025 | 0.68 | HTR1A (0.56) | ABCB1HTR1ASLC6A4EBPSIGMAR1 | |
| Cilobradine SCHEMBL1855245 | 0.68 | HCN4 (0.57) | SMPD1HTR1ASLC6A4SIGMAR1POLB | |
| Cilobradine SCHEMBL30169956 | 0.68 | HCN4 (0.57) | SMPD1HTR1ASLC6A4SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |