SCHEMBL9740689

SCHEMBL9740689

CCOC(CNC(=O)C[C@@H](Cc1coc2ccccc12)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](CC1CCCCC1)[C@H](O)c1ccco1)OCC

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9740696 1.00 REN (0.38) REN
SCHEMBL9740080 0.81 REN (0.48) REN
SCHEMBL9740075 0.81 REN (0.48) REN
SCHEMBL7277581 0.76 REN (0.49) REN
SCHEMBL7277586 0.76 REN (0.49) REN
SCHEMBL9740172 0.76 REN (0.51) REN
SCHEMBL9740169 0.76 REN (0.51) REN
SCHEMBL9739605 0.75 MMP2 (0.51) REN
SCHEMBL9739604 0.75 MMP2 (0.51) REN
SCHEMBL7305274 0.74 REN (0.46) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104869-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1992-04-14 US claimed