Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327118 | 0.84 | MLYCD (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6539244 | 0.79 | NPC1 (0.65) | NPC1RAB9ATRPM8ALDH1A1 | |
| SCHEMBL6305242 | 0.78 | RELA (0.57) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6538464 | 0.77 | SMN1; SMN2 (0.61) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10143988 | 0.76 | NPC1 (0.63) | MEN1KMT2ANPC1RAB9ATRPM8 | |
| SCHEMBL6148806 | 0.76 | MEN1 (0.61) | MEN1KMT2A | |
| SCHEMBL6765958 | 0.76 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9ATRPM8 | |
| SCHEMBL17230201 | 0.76 | TRPM8 (0.64) | MEN1KMT2ANPC1RAB9ATRPM8 | |
| SCHEMBL6657920 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL6538743 | 0.75 | NPC1 (0.52) | NPC1RAB9ATRPM8ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132317-A | Thiazolidinediones, Hypoglycemia Agents | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |