Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602254 | 0.79 | ALOX5 (0.50) | MAOBMAOAIMPDH2KDM4EMAPT | |
| SCHEMBL9739267 | 0.79 | MAPT (0.33) | MAPT | |
| SCHEMBL9740914 | 0.75 | TUBB1 (0.56) | MAOBKDM4E | |
| SCHEMBL9740778 | 0.75 | ALOX5 (0.36) | MAOBMAOARHEBCA12CA1 | |
| SCHEMBL9741209 | 0.74 | MAOB (0.36) | MAOBMAOAHTR1AHTR1DHTR1B | |
| SCHEMBL6345184 | 0.72 | HPGD (0.47) | KDM4EMAPTLTA4H | |
| SCHEMBL6015874 | 0.70 | MAOA (0.41) | MAOACA12CA1CA9 | |
| SCHEMBL4599898 | 0.68 | ALOX5 (0.50) | MAOBMAOAHTR1DIMPDH2KDM4E | |
| SCHEMBL6016024 | 0.68 | MAOA (0.36) | MAOAHTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL1968319 | 0.67 | MEN1 (0.47) | KDM4EMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |