Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739954 | 0.76 | ALDH1A1 (0.37) | NQO2ALDH1A1AXLMAPT | |
| SCHEMBL5865329 | 0.72 | KDM4E (0.46) | HSD17B10CA1NQO2HPGDALDH1A1 | |
| SCHEMBL9740846 | 0.70 | RXFP1 (0.38) | NQO2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9741024 | 0.67 | GRIN2D (0.35) | GPR35GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28426250 | 0.66 | CA2 (0.58) | CA2CA4GPR35HSD17B10CA1 | |
| SCHEMBL9740762 | 0.66 | CA2 (0.42) | CA2CA4GPR35HSD17B10CA1 | |
| SCHEMBL30697556 | 0.65 | CA2 (0.50) | CA2CA4GPR35HSD17B10CA1 | |
| SCHEMBL9740260 | 0.64 | PDE3B (0.40) | CA2HSD17B10CA1NQO2HPGD | |
| SCHEMBL3309764 | 0.64 | CA2 (0.45) | CA2CA4GPR35HSD17B10CA1 | |
| SCHEMBL6181005 | 0.64 | KDM4E (0.39) | HSD17B10NQO2HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |