Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319314 | 1.00 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7319306 | 1.00 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9272467 | 0.76 | GRM5 (0.41) | ALDH1A1HTTLMNA | |
| SCHEMBL9798245 | 0.76 | GRM5 (0.41) | ALDH1A1HTTLMNA | |
| SCHEMBL11105312 | 0.75 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL10244414 | 0.75 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11105319 | 0.75 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7361609 | 0.74 | ADORA2B (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7361604 | 0.74 | ADORA2B (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7321057 | 0.74 | ADORA2B (0.38) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |