Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036005 | 0.74 | CHRNB2 (0.40) | GRM5 | |
| SCHEMBL29263693 | 0.74 | CHRNB2 (0.40) | GRM5 | |
| SCHEMBL9741925 | 0.72 | HDAC3 (0.31) | — | |
| SCHEMBL9741725 | 0.69 | GRM5 (0.40) | GRM5 | |
| SCHEMBL17567286 | 0.69 | GRM5 (0.45) | GRM5 | |
| SCHEMBL5240290 | 0.69 | GRM5 (0.41) | GRM5 | |
| SCHEMBL102936 | 0.68 | GRM5 (0.42) | GRM5 | |
| Biphenyl SCHEMBL27555363 | 0.65 | CYP1A2 (0.37) | GRM5 | |
| SCHEMBL15870932 | 0.65 | GRM5 (0.59) | GRM5 | |
| SCHEMBL31286309 | 0.65 | GRM5 (0.59) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149698-A | Pyrimidinyl alkyleneoxy bronchodilator agent | GLAXO GROUP LIMITED (GB) | 1992-09-22 | — | — | US | disclosed |
| US-4996218-A | Bronchodilator, antiulcer agent, cardiovascular disorders | GLAXO GROUP LIMITED (GB) | 1991-02-26 | — | — | US | disclosed |
| EP-0303464-A2 | Chloroaniline derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |