Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439991 | 0.87 | CALM1 (0.44) | CYP3A4HPGDHTR2ACALM1BCL2 | |
| SCHEMBL960737 | 0.81 | CYP3A4 (0.46) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL962228 | 0.77 | MIF (0.54) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL6605569 | 0.77 | ALDH1A1 (0.44) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL10456439 | 0.77 | HTR2A (0.41) | CYP3A4HPGDHTR2ACALM1BCL2 | |
| SCHEMBL510928 | 0.77 | CYP3A4 (0.44) | CYP3A4HTR2ACALM1BCL2BCL2L1 | |
| SCHEMBL20027282 | 0.75 | CYP3A4 (0.51) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL2046670 | 0.74 | MIF (0.65) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL20027247 | 0.73 | MIF (0.42) | CYP3A4HPGDTRPA1ALDH1A1MIF | |
| SCHEMBL678579 | 0.73 | CALM1 (0.50) | CYP3A4HPGDALDH1A1HTR2ACALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084304-A | Heat resistant coating applied to a metal, a heat resistant material polymer such as a blend of a polyesterimide, a polyhydantoin, a polyamide, a polyamideimide copolymer and a polybismaleimide | BASF LACKE & FARBEN AG (DE) | 1992-01-28 | — | — | US | disclosed |