Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 6/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195622 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL6386027 | 0.86 | MIF (0.42) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL439991 | 0.84 | CALM1 (0.44) | CYP3A4HPGDALOX15DRD1HSD17B10 | |
| SCHEMBL10456439 | 0.81 | HTR2A (0.41) | CYP3A4HPGDCYP1A2ALOX15DRD1 | |
| SCHEMBL510928 | 0.81 | CYP3A4 (0.44) | CYP3A4CYP1A2HTR2ACALM1GABRA1 | |
| SCHEMBL29188871 | 0.81 | LTA4H (0.41) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL678579 | 0.77 | CALM1 (0.50) | ALDH1A1CYP3A4HPGDALOX15DRD1 | |
| SCHEMBL9742015 | 0.77 | CYP3A4 (0.44) | ALDH1A1CYP3A4HPGDCYP1A2DRD1 | |
| SCHEMBL21634029 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP3A4HPGDABCB11NR3C1 | |
| SCHEMBL945820 | 0.76 | GABRA1 (0.62) | ALDH1A1CYP3A4HPGDABCB11NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354592-B | 2-thioquinazolinone compound and preparation method and application thereof | 赣南师范大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-113354592-A | 2-thioquinazolinone compound and preparation method and application thereof | 赣南师范大学 | 2021-09-07 | — | — | CN | disclosed |
| US-20100212548-A1 | Immersion Liquid And Method For Preparing An Organic Compound For An Immersion Liquid | CARL ZEISS AG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100212548-A1 | Immersion Liquid And Method For Preparing An Organic Compound For An Immersion Liquid | CARL ZEISS AG (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-1458684-A2 | THERAPEUTIC HETEROCYCLES | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051276-A2 | THERAPEUTIC HETEROCYCLES | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100212548-A1 | Immersion Liquid And Method For Preparing An Organic Compound For An Immersion Liquid | F12, NR1H3, FLI1 | ALDH1A1 2122/4885CYP3A4 1375/4885HPGD 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.