Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CBX7 | O95931 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742640 | 0.91 | CHRM5 (0.46) | CHRM5TP53MDM2KMT2ASCN9A | |
| SCHEMBL9742083 | 0.88 | CHRM5 (0.43) | CHRM5MDM2KMT2ASLC6A4SLC6A2 | |
| SCHEMBL9742586 | 0.87 | HTT (0.38) | CHRM5KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9742140 | 0.86 | CHRM5 (0.49) | CHRM5KMT2AOPRD1OPRK1SLC6A4 | |
| SCHEMBL9742428 | 0.85 | LMNA (0.37) | CHRM5MDM2KMT2APARP1 | |
| SCHEMBL9743436 | 0.84 | GRIN1 (0.39) | CHRM5KMT2ASIGMAR1 | |
| SCHEMBL9743342 | 0.83 | PSEN1 (0.40) | CHRM5MDM2KMT2A | |
| SCHEMBL9744849 | 0.83 | PARP1 (0.46) | SIGMAR1PARP1 | |
| SCHEMBL9744919 | 0.81 | HTT (0.40) | CHRM5MDM2KMT2ASLC6A4SLC6A2 | |
| SCHEMBL9744852 | 0.80 | CHRM5 (0.44) | CHRM5OPRK1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |