Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740223 | 0.86 | CHRM5 (0.48) | CHRM5PARP1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9742640 | 0.86 | CHRM5 (0.46) | CHRM5PARP1KMT2ASLC6A4SLC6A9 | |
| SCHEMBL9742113 | 0.86 | CHRM5 (0.43) | CHRM5PARP1KMT2ASLC6A4SIGMAR1 | |
| SCHEMBL9744849 | 0.84 | PARP1 (0.46) | PARP1SIGMAR1 | |
| SCHEMBL9743611 | 0.84 | PARP1 (0.46) | CHRM5PARP1KMT2ASIGMAR1 | |
| SCHEMBL9739723 | 0.84 | LMNA (0.46) | CHRM5PARP1KMT2AOPRM1OPRD1 | |
| SCHEMBL9740279 | 0.81 | HTT (0.47) | CHRM5KMT2A | |
| SCHEMBL9739787 | 0.81 | CHRM5 (0.43) | CHRM5KMT2ASLC6A9OPRM1OPRD1 | |
| SCHEMBL9740111 | 0.80 | SLC6A2 (0.43) | CHRM5KMT2ASLC6A4OPRM1SLC6A2 | |
| SCHEMBL9739810 | 0.79 | PARP1 (0.47) | CHRM5PARP1SIGMAR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |