Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546097 | 0.93 | PTGER2 (0.34) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546442 | 0.84 | PTGER2 (0.37) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546166 | 0.79 | PPARG (0.33) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546204 | 0.77 | PPARG (0.36) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546383 | 0.77 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL9546101 | 0.73 | PPARG (0.33) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL10619325 | 0.71 | NFKB1 (0.37) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546377 | 0.70 | PTGER3 (0.33) | PTGER2PPARGPTGER4PTGER3PPARA | |
| SCHEMBL9546109 | 0.68 | PPARG (0.30) | PPARG | |
| SCHEMBL9546318 | 0.66 | TRPA1 (0.43) | PTGER2PPARGPTGER4PTGER3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |