Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765557 | 0.95 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL12961840 | 0.95 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL13951737 | 0.95 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL6161775 | 0.95 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL6163980 | 0.83 | KCNH2 (0.47) | MAPTHTTKCNH2KMT2APOLB | |
| SCHEMBL6163946 | 0.82 | KCNH2 (0.44) | NPSR1MAPTKCNH2KMT2APOLB | |
| SCHEMBL6978258 | 0.81 | HCAR3 (0.52) | MAPTHTTKCNH2KMT2APOLB | |
| SCHEMBL10726992 | 0.81 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL10726981 | 0.81 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A | |
| SCHEMBL10726985 | 0.81 | KCNH2 (0.42) | NPSR1MAPTHTTKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162553-A | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5066816-A | PROCESSES FOR PREPARING OPTICALLY ACTIVE 3,4-DIHYDRO-3,4-EPOXY-2H-1-BENZOPYRAN COMPOUNDS AND INTERMEDIATES THEREFOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0386640-A2 | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4644070-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-02-17 | — | — | US | disclosed |
| EP-0095316-B1 | PHARMACEUTICALLY ACTIVE AMINOBENZOPYRANS | BEECHAM GROUP PLC (GB) | 1986-12-03 | — | — | EP | disclosed |
| EP-0091748-B1 | ANTIHYPERTENSIVE BENZOPYRANOLS | BEECHAM GROUP PLC (GB) | 1986-06-18 | — | — | EP | disclosed |
| US-4568692-A | LOWERING BLOOD PRESSURE | BEECHAM GROUP P.L.C. | 1986-02-04 | — | — | US | disclosed |
| US-4542149-A | HYPOTENSIVE | BEECHAM GROUP P.L.C. (GB) | 1985-09-17 | — | — | US | disclosed |
| US-4481214-A | 4-Acylaminobenzopyrans useful as anti-hypertensive agents | BEECHAM GROUP P.L.C. (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |
| EP-0091748-A1 | Antihypertensive benzopyranols | BEECHAM GROUP PLC (GB) | 1983-10-19 | — | — | EP | disclosed |