Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12961840 | 0.87 | KCNH2 (0.42) | KCNH2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL6161775 | 0.87 | KCNH2 (0.42) | KCNH2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL13951737 | 0.87 | KCNH2 (0.42) | KCNH2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL14765557 | 0.87 | KCNH2 (0.42) | KCNH2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL6163980 | 0.86 | KCNH2 (0.47) | KCNH2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL9742503 | 0.82 | NPSR1 (0.41) | KCNH2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL6978258 | 0.82 | HCAR3 (0.52) | KCNH2ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6980817 | 0.80 | KCNH2 (0.56) | KCNH2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL27485566 | 0.79 | HCAR3 (0.41) | KCNH2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL6982472 | 0.77 | KCNH2 (0.55) | KCNH2ALDH1A1MAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212314-B1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6589983-B1 | Antiarrhythmic agents having the prolongation effect on the functional refractory period as a main function | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1212314-A1 | BENZOPYRAN DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001021610-A1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |