Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | RXRG | P48443 | 5/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744479 | 0.77 | NR1D1 (0.48) | ALDH1A1RXRAKDM4EMEN1LMNA | |
| SCHEMBL8065941 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL1278375 | 0.69 | BCL2L1 (0.52) | BCL2L1BADCYP19A1 | |
| SCHEMBL4250760 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1THRBKMT2A | |
| SCHEMBL19116376 | 0.69 | BCL2L1 (0.39) | BCL2L1BADMEN1KMT2A | |
| SCHEMBL1721640 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL22375238 | 0.69 | BCL2L1 (0.39) | BCL2L1BAD | |
| SCHEMBL1721952 | 0.68 | TRPM5 (0.44) | ALDH1A1 | |
| SCHEMBL9465746 | 0.68 | ALDH1A1 (0.44) | ALDH1A1POLB | |
| SCHEMBL1721723 | 0.68 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |