Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742808 | 0.77 | BCL2L1 (0.39) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4247872 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4250506 | 0.73 | DHFR (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21722418 | 0.72 | NR1D1 (0.44) | NR1D1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21733882 | 0.70 | NR1D1 (0.42) | NR1D1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7263632 | 0.70 | ALDH1A1 (0.52) | NR1D1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10512434 | 0.69 | CYP4F2 (0.55) | NR1D1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23088507 | 0.69 | MEN1 (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2115724 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7258110 | 0.68 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |