Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740226 | 0.71 | FABP4 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL7478248 | 0.69 | CYP1A2 (0.41) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9754273 | 0.66 | FABP4 (0.49) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9738282 | 0.66 | KDM4E (0.36) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL9741872 | 0.66 | KDM4E (0.39) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL25225285 | 0.63 | RAB9A (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9738267 | 0.62 | FABP4 (0.47) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL23657859 | 0.61 | LMNA (0.55) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL4197148 | 0.61 | NPC1 (0.81) | RAB9ASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL1735963 | 0.60 | KDM4E (0.41) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006979-A1 | NEW DIAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-04-30 | — | — | WO | disclosed |