Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744852 | 0.91 | CHRM5 (0.44) | CHRM5EPHX2OPRL1SLC6A4MAPT | |
| SCHEMBL9743820 | 0.88 | CHRM5 (0.45) | CHRM5EPHX2OPRL1HRH3 | |
| SCHEMBL9742794 | 0.87 | HTT (0.40) | CHRM5SLC6A4MAPTSLC6A3SLC6A2 | |
| SCHEMBL9738601 | 0.86 | CHRM5 (0.53) | CHRM5SLC6A4MAPTOPRM1 | |
| SCHEMBL9743551 | 0.85 | PSEN1 (0.40) | CHRM5MAPTOPRM1 | |
| SCHEMBL9743860 | 0.84 | HTT (0.41) | CHRM5MAPT | |
| SCHEMBL9745487 | 0.83 | SMN1; SMN2 (0.38) | CHRM5MAPT | |
| SCHEMBL9741939 | 0.81 | SMN1; SMN2 (0.43) | CHRM5 | |
| SCHEMBL9742640 | 0.80 | CHRM5 (0.46) | CHRM5SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9743255 | 0.79 | CHRM5 (0.40) | CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |