Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741164 | 0.86 | CHRM5 (0.49) | CHRM5MEN1KMT2ANPC1POLB | |
| SCHEMBL9744852 | 0.86 | CHRM5 (0.44) | CHRM5MAPTSLC6A4CCR2OPRM1 | |
| SCHEMBL9743002 | 0.86 | CHRM5 (0.46) | CHRM5MAPTSLC6A4OPRM1 | |
| SCHEMBL9739787 | 0.84 | CHRM5 (0.43) | CHRM5MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9739723 | 0.81 | LMNA (0.46) | CHRM5MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9740279 | 0.81 | HTT (0.47) | CHRM5MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9742140 | 0.79 | CHRM5 (0.49) | CHRM5SLC6A4KMT2AOPRM1 | |
| SCHEMBL9740111 | 0.78 | SLC6A2 (0.43) | CHRM5SLC6A4MEN1KMT2ANPC1 | |
| SCHEMBL9738615 | 0.77 | CHRM5 (0.46) | CHRM5MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9742164 | 0.76 | CHRM5 (0.47) | CHRM5MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |