Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.31 |
| ▸ | GLRB | P48167 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743167 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9743151 | 0.76 | APEX1 (0.45) | ALDH1A1MAPK1KDM4EMAPTGAA | |
| SCHEMBL9743755 | 0.73 | AKR1C3 (0.37) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9742189 | 0.72 | GLRA3 (0.38) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL11580777 | 0.68 | CA1 (0.38) | LCKFYN | |
| SCHEMBL5071955 | 0.67 | CYP3A4 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7217680 | 0.64 | ALDH1A1 (0.37) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7745596 | 0.64 | GABRP (0.42) | ALDH1A1KDM4EKMT2AMAPTHCAR2 | |
| SCHEMBL31512401 | 0.64 | LCK (0.70) | ALDH1A1MAPK1SMN1; SMN2LCKFYN | |
| SCHEMBL31512400 | 0.64 | LCK (0.70) | ALDH1A1MAPK1SMN1; SMN2LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082959-A | Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts | AMOCO CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |