Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743233 | 1.00 | CYP3A4 (0.45) | CYP3A4ALDH1A1RECQLPTGS2SELL | |
| SCHEMBL4631529 | 0.79 | CYP3A4 (0.63) | CYP3A4ALDH1A1RECQLPTGS2SELL | |
| SCHEMBL28890060 | 0.79 | LCK (0.59) | CYP3A4ALDH1A1PTGS2LCKKDM4E | |
| SCHEMBL4631536 | 0.79 | CYP3A4 (0.63) | CYP3A4ALDH1A1RECQLPTGS2SELL | |
| SCHEMBL9742780 | 0.78 | ALDH1A1 (0.68) | CYP3A4ALDH1A1RECQLLCKKDM4E | |
| SCHEMBL9742784 | 0.78 | ALDH1A1 (0.68) | CYP3A4ALDH1A1RECQLLCKKDM4E | |
| SCHEMBL4608757 | 0.77 | PTGS2 (0.54) | CYP3A4ALDH1A1PTGS2SELLSELP | |
| SCHEMBL4608754 | 0.77 | PTGS2 (0.54) | CYP3A4ALDH1A1PTGS2SELLSELP | |
| SCHEMBL8072537 | 0.75 | GABBR2 (0.58) | CYP3A4ALDH1A1RECQLPTGS2MEN1 | |
| SCHEMBL8072535 | 0.75 | GABBR2 (0.58) | CYP3A4ALDH1A1RECQLPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |